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What to expect?

A Safe and Effective Option

Mifeprex* is the only Food and Drug Administration (FDA)-approved non-surgical option for ending early pregnancy. More than 2 Million women in the United States have used Mifeprex since it was approved by the FDA in September 2000. Mifeprex is 92-95% effective for safely ending pregnancy (5-8% of women will need a surgical procedure to end the pregnancy or stop heavy bleeding).

How Mifeprex Works

Mifeprex is a pill that blocks a hormone, progesterone, which is needed for your pregnancy to continue. When followed by another medicine, misoprostol, Mifeprex ends early pregnancy.

Mifeprex is not approved for ending later pregnancies. Early pregnancy means it is 49 days (7 weeks) or less since your last menstrual period began. Mifeprex is taken orally and allows you to avoid anesthesia or surgery in most cases.

How to Take Mifeprex

Please read the Safety Information section before taking Mifeprex. The regimen for Mifeprex requires that a woman make three visits to her healthcare provider over a two-week period.

Day 1 at your provider’s office:

  • Read the Medication Guide.
  • Discuss the benefits and risks of using Mifeprex to end your pregnancy
  • If you decide Mifeprex is right for you, sign the Patient Agreement
  • After getting a physical exam, swallow 3 tablets of Mifeprex.

Day 3 at your provider's office:

  • Take 2 misoprostol tablets
  • Misoprostol may cause cramps, nausea, diarrhea, and other symptoms. Your provider may send you home with medicines for these symptoms. To read more about Mifeprex side effects, click here.

About Day 14 at your provider's office:

  • This follow-up visit is very important. You must return to the provider about 14 days after you have taken Mifeprex to be sure you are well and that you are not pregnant.
  • Your provider will check whether your pregnancy has completely ended. If it has not ended, there is a chance that there may be birth defects. If you are still pregnant, your provider will talk with you about the other choices you have, including a surgical procedure to end your pregnancy.

Counseling and Support

Mifeprex offers you a more private option, with support and counseling readily available throughout the process. If you have routine questions, you can call your provider’s staff during regular office hours. Your healthcare provider will give you a telephone number to call in case of an emergency and you should take your Medication Guide with you if you go to an emergency room or provider other than the one who prescribed your Mifeprex, so they know you are undergoing a medical abortion with Mifeprex.

After Mifeprex

You can become pregnant again soon after your pregnancy ends. If you do not want to become pregnant again, start using birth control as soon as your pregnancy ends or before you start having sexual intercourse again. You should discuss any questions about birth control with your healthcare provider as s/he will have the most specific information about your situation.

To view the downloaded forms, you need Adobe Acrobat Reader (a free program) installed on your computer. If you do not have this program installed on your computer, you can download it from Adobe's Web site.


Although cramping and bleeding are an expected part of ending a pregnancy, rarely, serious and potentially life-threatening bleeding, infections, or other problems can occur following a miscarriage, surgical abortion, medical abortion, or childbirth. Prompt medical attention is needed in these circumstances. Serious infection has resulted in death in a very small number of cases; in most of these cases misoprostol was used in the vagina. There is no information that use of Mifeprex and misoprostol caused these deaths. If you have any questions, concerns, or problems, or if you are worried about any side effects or symptoms, you should contact your provider.

Be sure to contact your provider promptly if you have any of the following:

Heavy Bleeding. Contact your provider right away if you bleed enough to soak through two thick full-size sanitary pads per hour for two consecutive hours or if you are concerned about heavy bleeding. In about 1 out of 100 women, bleeding can be so heavy that it requires a surgical procedure (surgical abortion/D&C) to stop it.

Abdominal Pain or “Feeling Sick”. If you have abdominal pain or discomfort, or you are “feeling sick”, including weakness, nausea, vomiting, or diarrhea, with or without fever, more than 24 hours after taking misoprostol, you should contact your provider without delay. These symptoms may be a sign of a serious infection or another problem (including an ectopic pregnancy, a pregnancy outside the womb).

Fever. In the days after treatment, if you have a fever of 100.4°F or higher that lasts for more than 4 hours, you should contact your provider right away. Fever may be a symptom of a serious infection or another problem (including an ectopic pregnancy).

Take your MEDICATION GUIDE with you. When you visit an emergency room or a provider who did not give you your Mifeprex, you should give them your MEDICATION GUIDE so that they understand that you are having a medical abortion with Mifeprex.

Mifeprex* is a registered trademark
of Danco Laboratories, LLC
1-877-4 Early Option
FDA approved since 2000.
A safe and effective non-surgical option for ending early pregnancy.