For Health Professionals

Mifeprex* is the only Food and Drug Administration (FDA) - approved non-surgical option for early abortion. More than 1.2 Million women in the United States have chosen this option since it was approved by the FDA in September 2000.

Taken orally in pill form and administered in the privacy of a doctor's office or clinic, Mifeprex is a safe and effective way to end early pregnancy. Mifeprex can be taken up to 49 days after the beginning of a woman’s last menstrual period; it allows a woman to act early when deciding to end a pregnancy.

To learn more about Mifeprex and how this option can be easily integrated with your standard office practice explore the links listed on the right.

IMPORTANT SAFETY INFORMATION

Serious and sometimes fatal infections and bleeding occur very rarely following spontaneous, surgical, and medical abortions, including following Mifeprex use. No causal relationship between the use of Mifeprex and misoprostol and these events has been established. A high index of suspicion is needed to rule out serious and rarely fatal infections (e.g. Clostridium sordellii) and sepsis that can present without fever, bacteremia or significant findings on a pelvic exam, with or without abdominal pain, but with leukocytosis with a marked left shift, tachycardia, hemoconcentration, and general malaise.

Cramping and bleeding are expected; bleeding may continue for 9-16 days. 5-8% of women will need a surgical procedure to end a pregnancy or stop heavy bleeding.

Patients should be counseled to seek immediate medical attention if they experience sustained fever (100.4° F or higher), severe abdominal pain, prolonged heavy vaginal bleeding, syncope or general malaise more than 24 hours after taking misoprostol.

Mifeprex should not be used in cases of confirmed or suspected ectopic pregnancy, as Mifeprex is not effective in terminating these pregnancies. Physicians may need to consider the possibility of a ruptured ectopic pregnancy, even if efforts were made to rule out an ectopic pregnancy, because an ectopic pregnancy may have been missed.